best anti aging supplement with nmn

Top 10 Proven Anti‑Aging Ingredients That Actually Work

Aging gracefully doesn’t have to mean surrendering to wrinkles, fatigue, or sagging skin. The key? Choosing supplements formulated with scientifically backed natural ingredients—many of which you’ll find in trusted platforms like Digistore24 and SellHealth. Here are the Top 10 ingredients that consistently deliver noticeable results:

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1. NMN (Nicotinamide Mononucleotide)

A vital precursor to NAD⁺, NMN enhances cellular energy and supports DNA repair. Featured in popular anti-aging supplements like Liposomal NMN by GenuinePurity®,  . Learn more in our Longevity & Cellular Health collection.

2. Spermidine

GenuinePurity® Spermidine contains 99% Pure Spermidine and is a clinically proven autophagy activator with liposomal encapsulation for maximum absorption & effectiveness.

  • Spermidine, a naturally occurring polyamine found in various foods such as wheat germ, soybeans, and aged cheese, offers a range of health benefits that make it an exciting focus of scientific research. One of its primary advantages is its ability to promote cellular autophagy, a process by which cells remove damaged components, thereby enhancing cellular renewal and overall health. This function is particularly significant in combating aging-related conditions, as autophagy declines with age.
  • Featuring:
  • Studies suggest that increased spermidine intake may improve cardiovascular health by reducing oxidative stress and inflammation, which are key contributors to heart disease. Furthermore, spermidine has been associated with enhanced cognitive function, as it supports neuronal health and may reduce the risk of neurodegenerative diseases like Alzheimer’s.

 

  • To maximize absorption, GenuinePurity® NMNH employs Liposomal Encapsulation Technology, which protects NMNH from degradation in the digestive system, ensuring efficient delivery to cells. Each capsule contains a clinically validated dose of 500 mg of 98% pure NMNH. The supplement is manufactured in the USA in cGMP-certified facilities, adhering to strict quality standards.​

 

  • Benefits of NMNH supplementation:
  • More energy, Better memory and thinking, 
  • Faster recovery after being active, 
  • Easier to maintain a healthy weight, 
  • Better sleep, 
  • Feel younger and stronger

Weight Loss & Anti-Aging blog.

3. Resveratrol (Trans‑Resveratrol)

A powerful antioxidant from grape skins that supports heart and skin health. Commonly paired with NMN or NAD boosters.

  • As you know, resveratrol (rez-veh-ruh-traal) is a potent antioxidant studied in depth for its fascinating health benefits. However, not all forms of resveratrol are created equal. In fact, many resveratrol products on the market provide no health benefit because it’s simply the “wrong” type.
  • Featuring:
  • You see, the chemical structure of resveratrol is identified in two isomeric forms, “cis” and “trans”. And in this state, resveratrol has limited oral bioavailability. The solution? Researchers have discovered that isolating trans-resveratrol not only increases bioavailability, but trans-resveratrol is the “superstar” that produces incredible health benefits associated with this important longevity compound. With GenuinePurity® Trans-Resveratrol you can rest assured that you’re getting the right type of resveratrol for the best results.

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4. Nicotine Riboside (NR)

GenuinePurity™ Liposomal Nicotinamide Riboside (NR) is a premium dietary supplement designed to boost NAD+ levels, a coenzyme essential for over 500 cellular functions including energy metabolism, DNA repair, and immune response. As NAD+ levels naturally decline with age, this supplement aims to counteract that process, promoting cellular regeneration, mitochondrial function, and overall longevity.​

  • Featuring:
  • Each serving delivers a clinically studied dose of 300mg of 98% pure NR, encapsulated using advanced liposomal technology. This method enhances bioavailability by protecting NR from degradation in the digestive tract, facilitating better absorption into the bloodstream, and improving cellular uptake. The liposomal delivery system ensures that more of the active ingredient reaches target cells, maximizing the supplement’s effectiveness.​
  • GenuinePurity™ distinguishes itself by providing third-party certification of its NR content, ensuring authenticity and quality. Manufactured in the USA within cGMP-certified facilities, the product is non-GMO, gluten-free, vegan, and free from common allergens and artificial additives.
  • Users are advised to take two capsules daily with a meal to experience benefits such as increased energy, enhanced cognitive function, improved sleep quality, and strengthened immune health.

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5. Fisetin

Genuine Purity™ Liposomal Fisetin contains 150mg of fisetin, enhanced with liposomal encapsulation for maximum absorption & effectiveness.

Fisetin is a flavonoid found in various fruits and vegetables. But perhaps the most intriguing fact is that this plant compound has a special “superpower” for eliminating “zombie” cells, also known as senescent cells.

  • Featuring:
  • Fisetin helps clear out senescent cells (damaged, non-dividing cells) which contribute to aging and chronic disease.
  • Supports healthy aging, cognitive function, and cellular health.
  • May help protect neurons and improve memory.

  • Considered for those at risk of or experiencing age-related cognitive decline, including early signs of dementia or Alzheimer’s.

  • Fisetin supports vascular health by reducing oxidative stress and inflammation in blood vessels.
  • Some studies suggest fisetin has anti-cancer effects by targeting cancer cell growth pathways.
  • It is not a treatment, but some integrative oncologists explore it in supportive care.

  • Fisetin is not classified as a conventional medicine, but rather a natural supplement. It doesn’t treat specific diseases in the way that pharmaceuticals do, but research suggests it may support the body in several therapeutic ways..

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